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Panama City To Chicago Flights

  • One-Way
  • Round-Trip
  • Multi-City

From

Indira Gandhi International Airport

To

Chhatrapati Shivaji International Airport

DEPARTURE DATE

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Friday

Return Date

Book a round trip
to save more

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TRAVELLER & CLASS

1 Traveller

Economy

March
April
August
September
October
November
December
January
February

March is by far the best month, wherein you can get cheapest flights for Panama City to Chicago. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.

disclDisclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

Best Flight From Panama City To Chicago

Avianca
Avianca

Panama City

22:05

Panama City

Tocumen International Airport

Sun , 05 Apr 2026

15h 10m
ellipse
1 Stop

Chicago

13:15

Chicago

Chicago O Hare International Airport

Mon, 06 Apr 2026

£182
Avianca
Avianca

Panama City

03:20

Panama City

Tocumen International Airport

Sun , 12 Apr 2026

09h 55m
ellipse
1 Stop

Chicago

13:15

Chicago

Chicago O Hare International Airport

Sun, 12 Apr 2026

£182
Avianca
Avianca

Panama City

09:45

Panama City

Tocumen International Airport

Sat , 14 Mar 2026

11h 35m
ellipse
1 Stop

Chicago

21:20

Chicago

Chicago O Hare International Airport

Sat, 14 Mar 2026

£182
Aeromexico
Aeromexico

Panama City

15:02

Panama City

Tocumen International Airport

Sun , 12 Apr 2026

23h 08m
ellipse
1 Stop

Chicago

14:10

Chicago

Chicago O Hare International Airport

Mon, 13 Apr 2026

£376
Aeromexico
Aeromexico

Panama City

14:48

Panama City

Tocumen International Airport

Sat , 14 Mar 2026

22h 57m
ellipse
1 Stop

Chicago

13:45

Chicago

Chicago O Hare International Airport

Sun, 15 Mar 2026

£376
Delta Airlines
Delta Airlines

Panama City

14:28

Panama City

Tocumen International Airport

Wed , 01 Apr 2026

18h 02m
ellipse
1 Stop

Chicago

08:30

Chicago

Chicago O Hare International Airport

Thu, 02 Apr 2026

£415
United Airlines
United Airlines

Panama City

15:30

Panama City

Tocumen International Airport

Sun , 05 Apr 2026

09h 15m
ellipse
1 Stop

Chicago

00:45

Chicago

Chicago O Hare International Airport

Mon, 06 Apr 2026

£419
United Airlines
United Airlines

Panama City

15:41

Panama City

Tocumen International Airport

Sat , 28 Mar 2026

16h 03m
ellipse
1 Stop

Chicago

07:44

Chicago

Chicago O Hare International Airport

Sun, 29 Mar 2026

£419
United Airlines
United Airlines

Panama City

15:30

Panama City

Tocumen International Airport

Sun , 12 Apr 2026

09h 15m
ellipse
1 Stop

Chicago

00:45

Chicago

Chicago O Hare International Airport

Mon, 13 Apr 2026

£419
Copa Airlines
Copa Airlines

Panama City

19:25

Panama City

Tocumen International Airport

Sun , 12 Apr 2026

05h 48m
ellipse
Non Stop

Chicago

01:13

Chicago

Chicago O Hare International Airport

Mon, 13 Apr 2026

£447
Copa Airlines
Copa Airlines

Panama City

19:20

Panama City

Tocumen International Airport

Sat , 14 Mar 2026

05h 44m
ellipse
Non Stop

Chicago

01:04

Chicago

Chicago O Hare International Airport

Sun, 15 Mar 2026

£447
ellipse

Early Morning Flight Panama City to Chicago

wallet
Cheapest Flight
Found
£182
group
Average Flight
Time
11h 35m
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Date/Time
14 Mar 2026
09:45 AM
plane
Airlines
Avianca
Ellipse

Late Night Flight Panama City to Chicago

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Cheapest Flight
Found
£182
group
Average Flight
Time
15h 10m
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Date/Time
05 Apr 2026
22:05 PM
plane
Airlines
Avianca

Flights from Panama City to Chicago with Easemytrip

Flying from Panama City to Chicago has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.

The air route between Panama City to Chicago is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between Tocumen International Airport (PTY) and Chicago O Hare International Airport (ORD). You can expect a flight distance of approximately 3753 km, and most direct services cover it in around 13:21.

Let’s take a closer look at everything you need to know before booking your flight from Panama City to Chicago.

Travel Overview: Panama City to Chicago

Flight Details Information
Route Distance 3753 km
Average Flight Time 13:21 hrs
Departure Airport Tocumen International Airport (PTY)
Arrival Airport Chicago O Hare International Airport (ORD)
Cabin Classes Available Economy Class, Premium Economy, Business Class, First Class
Direct Flights YES
Common Airlines Avianca, Aeromexico, Delta Airlines, United Airlines

The route is serviced regularly by both full-service and budget airlines, catering to all types of travellers — from those looking for no-frills budget options to those preferring business and first-class comfort. If you're flying for business, early morning weekday flights are a great choice, while leisure travellers often opt for weekend and evening departures.

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FAQs about flights from Panama City to Chicago

Are there direct flights from Panama City to Chicago?

How early should I book?

Which airlines offer the most frequent service?

Is it cheaper to fly round-trip or one-way?

Can I mix airlines for departure and return?

Is it possible to change or cancel my booking after confirmation?

Can I book additional baggage or in-flight services in advance?