February is by far the best month, wherein you can get cheapest flights for Medford to San Francisco. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.
Disclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

Medford
16:47
Medford
Rogue Valley International Medford Airport
Mon , 02 Feb 2026

San Francisco
21:25
San Francisco
San Francisco International Airport
Mon, 02 Feb 2026

Medford
15:45
Medford
Rogue Valley International Medford Airport
Mon , 02 Feb 2026

San Francisco
19:43
San Francisco
San Francisco International Airport
Mon, 02 Feb 2026

Medford
15:45
Medford
Rogue Valley International Medford Airport
Thu , 05 Feb 2026

San Francisco
19:43
San Francisco
San Francisco International Airport
Thu, 05 Feb 2026

Medford
14:00
Medford
Rogue Valley International Medford Airport
Mon , 02 Feb 2026

San Francisco
15:35
San Francisco
San Francisco International Airport
Mon, 02 Feb 2026

Medford
14:00
Medford
Rogue Valley International Medford Airport
Thu , 05 Feb 2026

San Francisco
15:35
San Francisco
San Francisco International Airport
Thu, 05 Feb 2026

Medford
05:09
Medford
Rogue Valley International Medford Airport
Thu , 05 Feb 2026

San Francisco
09:11
San Francisco
San Francisco International Airport
Thu, 05 Feb 2026

Medford
16:47
Medford
Rogue Valley International Medford Airport
Thu , 05 Feb 2026

San Francisco
21:25
San Francisco
San Francisco International Airport
Thu, 05 Feb 2026

Medford
14:00
Medford
Rogue Valley International Medford Airport
Sun , 08 Feb 2026

San Francisco
15:35
San Francisco
San Francisco International Airport
Sun, 08 Feb 2026

Medford
15:45
Medford
Rogue Valley International Medford Airport
Thu , 05 Feb 2026

San Francisco
19:43
San Francisco
San Francisco International Airport
Thu, 05 Feb 2026










Flying from Medford to San Francisco has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.
The air route between Medford to San Francisco is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between Rogue Valley International Medford Airport (MFR) and San Francisco International Airport (SFO). You can expect a flight distance of approximately 530 km, and most direct services cover it in around 03:19.
Let’s take a closer look at everything you need to know before booking your flight from Medford to San Francisco.
| Flight Details | Information |
|---|---|
| Route Distance | 530 km |
| Average Flight Time | 03:19 hrs |
| Departure Airport | Rogue Valley International Medford Airport (MFR) |
| Arrival Airport | San Francisco International Airport (SFO) |
| Cabin Classes Available | Economy Class, Premium Economy, Business Class, First Class |
| Direct Flights | YES |
| Common Airlines | Hawaiian Airlines, Alaska Airlines, United Airlines |
The route is serviced regularly by both full-service and budget airlines, catering to all types of travellers — from those looking for no-frills budget options to those preferring business and first-class comfort. If you're flying for business, early morning weekday flights are a great choice, while leisure travellers often opt for weekend and evening departures.