November is by far the best month, wherein you can get cheapest flights for Knoxville to Phoenix. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.
Disclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

TYS
15:59
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
21:46
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025

TYS
16:27
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
21:21
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025

TYS
11:45
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
16:31
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025

TYS
16:55
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
21:21
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025

TYS
18:18
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
22:30
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025

TYS
17:16
Knoxville
McGhee Tyson Airport
Thu , 06 Nov 2025

PHX
21:46
Phoenix
Phoenix Sky Harbor International Airport
Thu, 06 Nov 2025










Flying from Knoxville to Phoenix has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.
The air route between Knoxville to Phoenix is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between McGhee Tyson Airport (TYS) and Phoenix Sky Harbor International Airport (PHX). You can expect a flight distance of approximately 2568 km, and most direct services cover it in around 04:45.
Let’s take a closer look at everything you need to know before booking your flight from Knoxville to Phoenix.
| Flight Details | Information |
|---|---|
| Route Distance | 2568 km |
| Average Flight Time | 04:45 hrs |
| Departure Airport | McGhee Tyson Airport (TYS) |
| Arrival Airport | Phoenix Sky Harbor International Airport (PHX) |
| Cabin Classes Available | Economy Class, Premium Economy, Business Class, First Class |
| Direct Flights | NO |
| Common Airlines | Delta Airlines, American Airlines, United Airlines |
The route is serviced regularly by both full-service and budget airlines, catering to all types of travellers — from those looking for no-frills budget options to those preferring business and first-class comfort. If you're flying for business, early morning weekday flights are a great choice, while leisure travellers often opt for weekend and evening departures.