November is by far the best month, wherein you can get cheapest flights for Denver to Santa Ana. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.
Disclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

DEN
18:20
Denver
Denver International Airport
Mon , 17 Nov 2025

SNA
22:28
Santa Ana
John Wayne International Airport
Mon, 17 Nov 2025

DEN
05:20
Denver
Denver International Airport
Mon , 17 Nov 2025

SNA
08:49
Santa Ana
John Wayne International Airport
Mon, 17 Nov 2025

DEN
05:30
Denver
Denver International Airport
Fri , 07 Nov 2025

SNA
08:52
Santa Ana
John Wayne International Airport
Fri, 07 Nov 2025

DEN
15:37
Denver
Denver International Airport
Fri , 07 Nov 2025

SNA
21:30
Santa Ana
John Wayne International Airport
Fri, 07 Nov 2025

DEN
06:14
Denver
Denver International Airport
Sun , 23 Nov 2025

SNA
12:00
Santa Ana
John Wayne International Airport
Sun, 23 Nov 2025

DEN
11:31
Denver
Denver International Airport
Mon , 17 Nov 2025

SNA
17:08
Santa Ana
John Wayne International Airport
Mon, 17 Nov 2025

DEN
06:14
Denver
Denver International Airport
Fri , 28 Nov 2025

SNA
12:00
Santa Ana
John Wayne International Airport
Fri, 28 Nov 2025

DEN
07:50
Denver
Denver International Airport
Fri , 07 Nov 2025

SNA
09:23
Santa Ana
John Wayne International Airport
Fri, 07 Nov 2025

DEN
07:45
Denver
Denver International Airport
Fri , 07 Nov 2025

SNA
11:40
Santa Ana
John Wayne International Airport
Fri, 07 Nov 2025

DEN
08:00
Denver
Denver International Airport
Fri , 21 Nov 2025

SNA
16:22
Santa Ana
John Wayne International Airport
Fri, 21 Nov 2025

DEN
11:31
Denver
Denver International Airport
Fri , 07 Nov 2025

SNA
17:08
Santa Ana
John Wayne International Airport
Fri, 07 Nov 2025










Flying from Denver to Santa Ana has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.
The air route between Denver to Santa Ana is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between Denver International Airport (DEN) and John Wayne International Airport (SNA). You can expect a flight distance of approximately 1359 km, and most direct services cover it in around 04:51.
Let’s take a closer look at everything you need to know before booking your flight from Denver to Santa Ana.
| Flight Details | Information |
|---|---|
| Route Distance | 1359 km |
| Average Flight Time | 04:51 hrs |
| Departure Airport | Denver International Airport (DEN) |
| Arrival Airport | John Wayne International Airport (SNA) |
| Cabin Classes Available | Economy Class, Premium Economy, Business Class, First Class |
| Direct Flights | YES |
| Common Airlines | Delta Airlines, Hawaiian Airlines, Alaska Airlines, United Airlines |
The route is serviced regularly by both full-service and budget airlines, catering to all types of travellers — from those looking for no-frills budget options to those preferring business and first-class comfort. If you're flying for business, early morning weekday flights are a great choice, while leisure travellers often opt for weekend and evening departures.