October is by far the best month, wherein you can get cheapest flights for Charleston to Brussels. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.
Disclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

CHS
11:40
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
08:55
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
20:17
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
07:50
Brussels
Brussels Airport
Sun, 21 Dec 2025

CHS
11:05
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
07:50
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
14:50
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
10:10
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
14:50
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
07:15
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
14:50
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
07:15
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
14:50
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
07:15
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
11:01
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
10:50
Brussels
Brussels Airport
Sat, 20 Dec 2025

CHS
17:46
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
09:40
Brussels
Brussels Airport
Sun, 21 Dec 2025

CHS
12:53
Charleston
Charleston International Airport
Fri , 19 Dec 2025

BRU
09:00
Brussels
Brussels Airport
Sat, 20 Dec 2025










Flying from Charleston to Brussels has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.
The air route between Charleston to Brussels is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between Charleston International Airport (CHS) and Brussels Airport (BRU). You can expect a flight distance of approximately 6875 km, and most direct services cover it in around 22:31.
Let’s take a closer look at everything you need to know before booking your flight from Charleston to Brussels.
| Flight Details | Information |
|---|---|
| Route Distance | 6875 km |
| Average Flight Time | 22:31 hrs |
| Departure Airport | Charleston International Airport (CHS) |
| Arrival Airport | Brussels Airport (BRU) |
| Cabin Classes Available | Economy Class, Premium Economy, Business Class, First Class |
| Direct Flights | NO |
| Common Airlines | United Airlines, Air Canada, Lufthansa, Brussels Airlines |
The route is serviced regularly by both full-service and budget airlines, catering to all types of travellers — from those looking for no-frills budget options to those preferring business and first-class comfort. If you're flying for business, early morning weekday flights are a great choice, while leisure travellers often opt for weekend and evening departures.