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Panama City To Frankfurt Flights

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November is by far the best month, wherein you can get cheapest flights for Panama City to Frankfurt. Meanwhile, is perceived as the expensive month due to the varying factors. That’s why it’s highly advised to make advanced online flight booking to save huge amounts of money.

disclDisclaimer - All the above-mentioned fares were found within last 48 hrs. The displayed fares are based on historical data and are subject to change. The fares cannot be guaranteed at the time of booking.

Best Flight From Panama City To Frankfurt

KLM Royal Dutch AirlinesKLM Royal Dutch Airlines
Panama City
18:45
12 Nov 2026
12h 50m
1 Stop
Frankfurt
13:35
13 Nov 2026
£5535
Air FranceAir France
Panama City
22:30
12 Nov 2026
17h 35m
1 Stop
Frankfurt
22:05
13 Nov 2026
£5547
IberiaIberia
Panama City
11:54
12 Nov 2026
24h 56m
2 Stop
Frankfurt
18:50
13 Nov 2026
£5574
Air EuropaAir Europa
Panama City
21:30
12 Nov 2026
14h 25m
1 Stop
Frankfurt
17:55
13 Nov 2026
£5581
AviancaAvianca
Panama City
18:10
12 Nov 2026
18h 40m
2 Stop
Frankfurt
18:50
13 Nov 2026
£5608
Copa AirlinesCopa Airlines
Panama City
13:57
12 Nov 2026
15h 53m
1 Stop
Frankfurt
11:50
13 Nov 2026
£5723
United AirlinesUnited Airlines
Panama City
10:00
12 Nov 2026
17h 10m
1 Stop
Frankfurt
09:10
13 Nov 2026
£6036
AviancaAvianca
Panama City
18:10
12 Nov 2026
15h 45m
1 Stop
Frankfurt
15:55
13 Nov 2026
£6048
LufthansaLufthansa
Panama City
18:30
12 Nov 2026
15h 25m
1 Stop
Frankfurt
15:55
13 Nov 2026
£6048
Copa AirlinesCopa Airlines
Panama City
18:34
12 Nov 2026
14h 01m
1 Stop
Frankfurt
14:35
13 Nov 2026
£6063
AeromexicoAeromexico
Panama City
14:47
12 Nov 2026
17h 58m
1 Stop
Frankfurt
14:45
13 Nov 2026
£6089

Early Morning Flight Panama City to Frankfurt

cheap flight

Cheapest Flight Found

£6036
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Cheapest Month To Fly

12 Nov 2026
10:00 AM
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Airlines

United Airlines
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Average Flight Time

17h 10m

Late Night Flight Panama City to Frankfurt

cheap flight

Cheapest Flight Found

£5547
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Cheapest Month To Fly

12 Nov 2026
22:30 PM
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Airlines

Air France
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Average Flight Time

17h 35m

Flights from Panama City to Frankfurt with Easemytrip

Flying from Panama City to Frankfurt has never been easier. Whether you’re planning a short business trip, a weekend getaway, or reconnecting with family and friends, Easemytrip brings you the best deals, seamless booking, and flexible options for this popular flight route. Our platform is built to help travellers like you compare flight prices, explore direct and connecting options, and find the perfect departure time — all within a few clicks.

The air route between Panama City to Frankfurt is one of the most frequently travelled, offering reliable services from top airlines and excellent connectivity between Tocumen International Airport (PTY) and Frankfurt am Main Airport (FRA). You can expect a flight distance of approximately 9090 km, and most direct services cover it in around 23:17.

Let’s take a closer look at everything you need to know before booking your flight from Panama City to Frankfurt.

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FAQs about flights from Panama City to Frankfurt

Are there direct flights from Panama City to Frankfurt?

How early should I book?

Which airlines offer the most frequent service?

Is it cheaper to fly round-trip or one-way?

Can I mix airlines for departure and return?

Is it possible to change or cancel my booking after confirmation?

Can I book additional baggage or in-flight services in advance?


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